Housed in a Neoclassical-style castle which once served the aristocratic Thun-Hohenstein family as a hunting lodge, the museum presents a number of exhibitions featuring the region's large holdings. In addition to the natural history objects in the permanent exhibition "Birds of the Děčín Region", there is a display of the results of archaeological investigation into the town's history, as well as a historical survey of the development of navigation on the river Elbe. Particularly well worth a visit is the exhibition complex "Gothic Sculpture in the Děčín Region", which comprises a unique collection of objects from that period. In the display entitled "A Stroll through Děčín" visitors are introduced to various places of importance in the town. The museum's inner courtyard features a lapidarium and an arboretum.
The main train station Děčín directions_railway directions_bus is only 200m away from the museum.